The December issue of Discover magazine has a list, "here in one place, the 25 greatest science books ever written." There are also eight honorable mentions. I won't reveal the secret of the #1 book, but it was a tie, with both books written by the same author. With the long Thanksgiving break, you might want to review the list and catch up with the one or two you have not yet read.
(Vairo Library has a paper copy, the online version is at:
http://www.discover.com/issues/dec-06/features/25-greatest-science-books//)